Bt produces a protein that is harmful to the digestive system of a caterpillar pest. When the caterpillar feeds on the Bt cotton plant, its digestive system is weakened, making it unable to feed and it eventually dies. The mode of action works the same way in maize, cowpea and other crops. Bt is very specific and not harmful to humans and other animals. It has been used in organic farming as a spray for over 50 years to control insect pests.